Anti-Pecam1 Antibody

Rs. 68,577.00
SKU stj73612

General Information

Product name Anti-Pecam1 Antibody
Short Description Goat polyclonal to Pecam1 / CD31 (mouse)
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-Pecam1 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 81.3 kDa
Database Links
Alternative Names Anti-Pecam1 / CD31 (mouse) Antibody
Function Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions (By similarity), Tyr-679 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes (By similarity), Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions (By similarity), Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils (By similarity), Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal (By similarity), Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells
Cellular Localization Cell membrane,
Tissue Specificity Isoform 1 and isoform 3 are expressed in lung and platelets,
Swiss-Prot Key

 

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