Anti-PFN2 Antibody

Rs. 45,619.00
SKU stj24965

General Information

Product name Anti-PFN2 Antibody
Short Description Rabbit polyclonal to PFN2
Description The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-PFN2 Antibody
Immunogen A synthetic peptide of human PFN2
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 15 kDa
Database Links
Alternative Names PFN2Profilin-2 antibodyProfilin IIPFN2
Function Binds to actin and affects the structure of the cytoskeleton, At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations, By binding to PIP2, it inhibits the formation of IP3 and DG
Cellular Localization Cytoplasm, cytoskeleton
Tissue Specificity Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver
Swiss-Prot Key

 

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