Anti-PHGDH Antibody

Rs. 61,689.00
SKU stj24981

General Information

Product name Anti-PHGDH Antibody
Short Description Rabbit polyclonal to PHGDH
Description This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.
Applications WB,IHC,FC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:100
FC 1:20 - 1:50
Protein Name Anti-PHGDH Antibody
Immunogen A synthetic peptide of human PHGDH
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 56.7 kDa
Database Links
Alternative Names PHGDHD-3-phosphoglycerate dehydrogenase antibody3-PGDHPHGDH antibodyPGDH3
Function Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway, Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate.
Cellular Localization
Tissue Specificity
Swiss-Prot Key

 

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