Anti-Phospho-4E-BP1 (T69) antibody

Rs. 50,211.00
SKU stj90163

General Information

Product name Anti-Phospho-4E-BP1 (T69) antibody
Short Description
Description Rabbit polyclonal to Phospho-4E-BP1 (T69).
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000
Protein Name Anti-Phospho-4E-BP1 (T69) antibody
Immunogen Synthesized peptide derived from human 4E-BP1 around the phosphorylation site of T46.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 12 kDa
Database Links
Alternative Names Phospho-4E-BP1 (T69)
Eukaryotic translation initiation factor 4E-binding protein 1 antibody
4E-BP1 antibody
eIF4E-binding protein 1 antibody
Phosphorylated heat- and acid-stable protein regulated by insulin 1 antibody
PHAS-I antibody
Function Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Cellular Localization
Tissue Specificity
Swiss-Prot Key

 

You recently viewed

Clear recently viewed