Anti-Phospho-AR (S94) antibody

Rs. 50,211.00
SKU stj91328

General Information

Product name Anti-Phospho-AR (S94) antibody
Short Description
Description Rabbit polyclonal to Phospho-AR (S94).
Applications IF,ELISA
Dilution range IF 1:200-1:1000ELISA 1:5000
Protein Name Anti-Phospho-AR (S94) antibody
Immunogen Synthesized peptide derived from human AR around the phosphorylation site of S94.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 99 kDa
Database Links
Alternative Names Phospho-AR (S94)
Androgen receptor antibody
Dihydrotestosterone receptor antibody
Nuclear receptor subfamily 3 group C member 4 antibody
DHTR antibody
NR3C4 antibody
Function Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. Isoform 3 and isoform 4 lack the C-terminal ligand-binding domain and may therefore constitutively activate the transcription of a specific set of genes independently of steroid hormones.
Cellular Localization Nucleus Cytoplasm. Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RACK1.
Tissue Specificity Isoform 2 is mainly expressed in heart and skeletal muscle . Isoform 3 is expressed by basal and stromal cells of prostate (at protein level) .
Swiss-Prot Key

 

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