Anti-Phospho-Bcl-2 (S70) antibody

Rs. 50,211.00
SKU stj90652

General Information

Product name Anti-Phospho-Bcl-2 (S70) antibody
Short Description
Description Rabbit polyclonal to Phospho-Bcl-2 (S70).
Applications WB,ELISA
Dilution range WB 1:500-1:2000ELISA 1:40000
Protein Name Anti-Phospho-Bcl-2 (S70) antibody
Immunogen Synthesized peptide derived from human Bcl-2 around the phosphorylation site of S70.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 26 kDa
Database Links
Alternative Names Phospho-Bcl-2 (S70)
Apoptosis regulator Bcl-2 antibody
Function Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release .
Cellular Localization Mitochondrion outer membrane Nucleus membrane Endoplasmic reticulum membrane
Tissue Specificity Expressed in a variety of tissues.
Swiss-Prot Key

 

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