| Product name |
Anti-Phospho-BCR-(Y177) Antibody |
| Short Description |
Rabbit Polyclonal to PhosphoBCR(Y177) |
| Description |
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. |
| Applications |
WB |
| Dilution range |
WB 1:500 - 1:2000 |
| Protein Name |
Anti-Phospho-BCR-(Y177) Antibody |
| Immunogen |
A phospho specific peptide corresponding to residues surrounding Y177 of human BCR |
| Storage Instruction |
Store at -20℃. Avoid freeze / thaw cycles. |
| Type of Usage |
For Research Use Only (RUO). |
