Anti-Phospho-BLM (T99) antibody

Rs. 50,211.00
SKU stj91066

General Information

Product name Anti-Phospho-BLM (T99) antibody
Short Description
Description Rabbit polyclonal to Phospho-BLM (T99).
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000
Protein Name Anti-Phospho-BLM (T99) antibody
Immunogen Synthesized peptide derived from human BLM around the phosphorylation site of T99.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 159 kDa
Database Links
Alternative Names Phospho-BLM (T99)
Bloom syndrome protein antibody
DNA helicase, RecQ-like type 2 antibody
RecQ2 antibody
RecQ protein-like 3 antibody
RECQ2 antibody
RECQL3 antibody
Function Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE).
Cellular Localization Nucleus. Together with SPIDR, is redistributed in discrete nuclear DNA damage-induced foci following hydroxyurea (HU) or camptothecin (CPT) treatment. Accumulated at sites of DNA damage in a RMI complex- and SPIDR-dependent manner.
Tissue Specificity
Swiss-Prot Key

 

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