Anti-Phospho-Caspase-9 (S144) antibody

Rs. 50,211.00
SKU stj90886

General Information

Product name Anti-Phospho-Caspase-9 (S144) antibody
Short Description
Description Rabbit polyclonal to Phospho-Caspase-9 (S144).
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000
Protein Name Anti-Phospho-Caspase-9 (S144) antibody
Immunogen Synthesized peptide derived from human Caspase-9 around the phosphorylation site of S144.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 35 kDa
Database Links
Alternative Names Phospho-Caspase-9 (S144)
Caspase-9 antibody
CASP-9 antibody
Apoptotic protease Mch-6 antibody
Apoptotic protease-activating factor 3 antibody
APAF-3 antibody
ICE-like apoptotic protease 6 antibody
ICE-LAP6 antibody
Caspase-9 subunit p35 antibody
Caspase-9 subunit p10 antibody
MCH6 antibody
Function Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).; Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Cellular Localization
Tissue Specificity Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes.
Swiss-Prot Key

 

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