Anti-Phospho-CKR-5 (S349) antibody

Rs. 50,211.00
SKU stj90450

General Information

Product name Anti-Phospho-CKR-5 (S349) antibody
Short Description
Description Rabbit polyclonal to Phospho-CKR-5 (S349).
Applications WB,ELISA
Dilution range WB 1:500-1:2000ELISA 1:5000
Protein Name Anti-Phospho-CKR-5 (S349) antibody
Immunogen Synthesized peptide derived from human CKR-5 around the phosphorylation site of S349.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 40 kDa
Database Links
Alternative Names Phospho-CKR-5 (S349)
C-C chemokine receptor type 5 antibody
C-C CKR-5 antibody
CC-CKR-5 antibody
CCR-5 antibody
CHEMR13 antibody
HIV-1 fusion coreceptor antibody
CD antigen CD195 antibody
CMKBR5 antibody
Function Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates. (Microbial infection) Acts as a receptor for human immunodeficiency virus-1/HIV-1.
Cellular Localization Cell membrane
Tissue Specificity Highly expressed in spleen, thymus, in the myeloid cell line THP-1, in the promyeloblastic cell line KG-1a and on CD4+ and CD8+ T-cells. Medium levels in peripheral blood leukocytes and in small intestine. Low levels in ovary and lung.
Swiss-Prot Key

 

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