Anti-Phospho-Connexin 43 (S368) antibody

Rs. 50,211.00
SKU stj90231

General Information

Product name Anti-Phospho-Connexin 43 (S368) antibody
Short Description
Description Rabbit polyclonal to Phospho-Connexin 43 (S368).
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000
Protein Name Anti-Phospho-Connexin 43 (S368) antibody
Immunogen Synthesized peptide derived from human Connexin 43 around the phosphorylation site of S368.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 43 kDa
Database Links
Alternative Names Phospho-Connexin 43 (S368)
Gap junction alpha-1 protein antibody
Connexin-43 antibody
Cx43 antibody
Gap junction 43 kDa heart protein antibody
GJAL antibody
Function Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract . May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles .
Cellular Localization Cell membrane Cell junction, gap junction Endoplasmic reticulum. Localizes at the intercalated disk (ICD) in cardiomyocytes and the proper localization at ICD is dependent on TMEM65.
Tissue Specificity Expressed in the heart and fetal cochlea.
Swiss-Prot Key

 

You recently viewed

Clear recently viewed