Anti-Phospho-Cytokeratin 18 (S52) antibody

Rs. 50,211.00
SKU stj90707

General Information

Product name Anti-Phospho-Cytokeratin 18 (S52) antibody
Short Description
Description Rabbit polyclonal to Phospho-Cytokeratin 18 (S52).
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000
Protein Name Anti-Phospho-Cytokeratin 18 (S52) antibody
Immunogen Synthesized peptide derived from human Cytokeratin 18 around the phosphorylation site of S52.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 48 kDa
Database Links
Alternative Names Phospho-Cytokeratin 18 (S52)
Keratin, type I cytoskeletal 18 antibody
Cell proliferation-inducing gene 46 protein antibody
Cytokeratin-18 antibody
CK-18 antibody
Keratin-18 antibody
K18 antibody
CYK18 antibody
PIG46 antibody
Function Involved in the uptake of thrombin-antithrombin complexes by hepatic cells . When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
Cellular Localization Cytoplasm, perinuclear region. Nucleus, nucleolus.
Tissue Specificity Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.
Swiss-Prot Key

 

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