Anti-Phospho-DNA Ligase IV (T650) antibody

Rs. 50,211.00
SKU stj91183

General Information

Product name Anti-Phospho-DNA Ligase IV (T650) antibody
Short Description
Description Rabbit polyclonal to Phospho-DNA Ligase IV (T650).
Applications IHC,ELISA
Dilution range IHC 1:100-1:300ELISA 1:10000
Protein Name Anti-Phospho-DNA Ligase IV (T650) antibody
Immunogen Synthesized peptide derived from human DNA Ligase IV around the phosphorylation site of T650.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 133 kDa
Database Links
Alternative Names Phospho-DNA Ligase IV (T650)
DNA ligase 4 antibody
DNA ligase IV antibody
Polydeoxyribonucleotide synthase antibody
ATP 4 antibody
Function Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Cellular Localization Nucleus.
Tissue Specificity Testis, thymus, prostate and heart.
Swiss-Prot Key

 

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