Anti-Phospho-EphA3/4/5 (Y779/833) antibody

Rs. 50,211.00
SKU stj91201

General Information

Product name Anti-Phospho-EphA3/4/5 (Y779/833) antibody
Short Description
Description Rabbit polyclonal to Phospho-EphA3/4/5 (Y779/833).
Applications IHC,ELISA
Dilution range IHC 1:100-1:300ELISA 1:10000
Protein Name Anti-Phospho-EphA3/4/5 (Y779/833) antibody
Immunogen Synthesized peptide derived from human EphA3/4/5 around the phosphorylation site of Y779/833.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 110 kDa
Database Links
Alternative Names Phospho-EphA3/4/5 (Y779/833)
Ephrin type-A receptor 3 antibody
EPH-like kinase 4 antibody
EK4 antibody
hEK4 antibody
HEK antibody
Human embryo kinase antibody
Tyrosine-protein kinase TYRO4 antibody
Tyrosine-protein kinase receptor ETK1 antibody
Eph-like tyrosine kinase 1 antibody
ETK antibody
ETK1 antibody
HEK antibody
TYRO4 antibody
Function Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5. Upon activation by EFNA5 regulates cell-cell adhesion, cytoskeletal organization and cell migration. Plays a role in cardiac cells migration and differentiation and regulates the formation of the atrioventricular canal and septum during development probably through activation by EFNA1. Involved in the retinotectal mapping of neurons. May also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.
Cellular Localization Isoform 1: Cell membrane Isoform 2: Secreted
Tissue Specificity Widely expressed. Highest level in placenta.
Swiss-Prot Key

 

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