Anti-Phospho-FADD (S191) antibody

Rs. 50,211.00
SKU stj90998

General Information

Product name Anti-Phospho-FADD (S191) antibody
Short Description
Description Rabbit polyclonal to Phospho-FADD (S191).
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000
Protein Name Anti-Phospho-FADD (S191) antibody
Immunogen Synthesized peptide derived from human FADD around the phosphorylation site of S194.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 25 kDa
Database Links
Alternative Names Phospho-FADD (S191)
FAS-associated death domain protein antibody
FAS-associating death domain-containing protein antibody
Growth-inhibiting gene 3 protein antibody
Mediator of receptor induced toxicity antibody
Protein FADD antibody
MORT1 antibody
GIG3 antibody
Function Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Cellular Localization
Tissue Specificity Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes.
Swiss-Prot Key

 

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