Anti-Phospho-GluR4 (S862) antibody

Rs. 50,211.00
SKU stj90900

General Information

Product name Anti-Phospho-GluR4 (S862) antibody
Short Description
Description Rabbit polyclonal to Phospho-GluR4 (S862).
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000
Protein Name Anti-Phospho-GluR4 (S862) antibody
Immunogen Synthesized peptide derived from human GluR4 around the phosphorylation site of S862.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 100 kDa
Database Links
Alternative Names Phospho-GluR4 (S862)
Glutamate receptor 4 antibody
GluR-4 antibody
GluR4 antibody
AMPA-selective glutamate receptor 4 antibody
GluR-D antibody
Glutamate receptor ionotropic, AMPA 4 antibody
GluA4 antibody
GLUR4 antibody
Function Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Cellular Localization Cell membrane. Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane. Multi-pass membrane protein. Cell projection, dendrite. Interaction with CNIH2, CNIH3 and PRKCG promotes cell surface expression.
Tissue Specificity
Swiss-Prot Key

 

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