Anti-Phospho-HSP27 (S15) antibody

Rs. 50,211.00
SKU stj90294

General Information

Product name Anti-Phospho-HSP27 (S15) antibody
Short Description
Description Rabbit polyclonal to Phospho-HSP27 (S15).
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000
Protein Name Anti-Phospho-HSP27 (S15) antibody
Immunogen Synthesized peptide derived from human HSP27 around the phosphorylation site of S15.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Monkey
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 26 kDa
Database Links
Alternative Names Phospho-HSP27 (S15)
Heat shock protein beta-1 antibody
HspB1 antibody
28 kDa heat shock protein antibody
Estrogen-regulated 24 kDa protein antibody
Heat shock 27 kDa protein antibody
HSP 27 antibody
Stress-responsive protein 27 antibody
SRP27 antibody
HSP27 antibody
HSP28 antibody
Function Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state . Plays a role in stress resistance and actin organization . Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins .
Cellular Localization Cytoplasm Nucleus Cytoplasm, cytoskeleton, spindle. Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Tissue Specificity Detected in all tissues tested: skeletal muscle, heart, aorta, large intestine, small intestine, stomach, esophagus, bladder, adrenal gland, thyroid, pancreas, testis, adipose tissue, kidney, liver, spleen, cerebral cortex, blood serum and cerebrospinal fluid. Highest levels are found in the heart and in tissues composed of striated and smooth muscle.
Swiss-Prot Key

 

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