Anti-Phospho-IL-4Rα (Y497) antibody

Rs. 50,211.00
SKU stj90720

General Information

Product name Anti-Phospho-IL-4Rα (Y497) antibody
Short Description
Description Rabbit polyclonal to Phospho-IL-4Rα (Y497).
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000
Protein Name Anti-Phospho-IL-4Rα (Y497) antibody
Immunogen Synthesized peptide derived from human IL-4Rα around the phosphorylation site of Y497.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 90 kDa
Database Links
Alternative Names Phospho-IL-4Ra (Y497)
Interleukin-4 receptor subunit alpha antibody
IL-4 receptor subunit alpha antibody
IL-4R subunit alpha antibody
IL-4R-alpha antibody
IL-4RA antibody
CD antigen CD124 antibody
Soluble interleukin-4 receptor subunit alpha antibody
Soluble IL-4 receptor subunit alpha antibody
Soluble IL-4R-alpha antibody
sIL4Ralpha/prot antibody
IL-4-binding protein antibody
IL4-BP antibodyA antibody
582J2.1 antibody
Function Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells.
Cellular Localization Cell membrane. Single-pass type I membrane protein.. Isoform 2: Secreted.
Tissue Specificity Isoform 1 and isoform 2 are highly expressed in activated T-cells.
Swiss-Prot Key

 

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