Anti-Phospho-KIR5.1 (S416) antibody

Rs. 50,211.00
SKU stj91098

General Information

Product name Anti-Phospho-KIR5.1 (S416) antibody
Short Description
Description Rabbit polyclonal to Phospho-KIR5.1 (S416).
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:5000
Protein Name Anti-Phospho-KIR5.1 (S416) antibody
Immunogen Synthesized peptide derived from human KIR5.1 around the phosphorylation site of S416.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 48 kDa
Database Links
Alternative Names Phospho-KIR5.1 (S416)
Inward rectifier potassium channel 16 antibody
Inward rectifier K antibody
+ channel Kir5.1 antibody
Potassium channel, inwardly rectifying subfamily J member 16 antibody
Function Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance. In the kidney, together with KCNJ10, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules .
Cellular Localization Membrane. In kidney distal convoluted tubules, located in the basolateral membrane in the presence of KCNJ10.
Tissue Specificity Widely expressed, with highest levels in adult and fetal kidney (at protein level). In the kidney, expressed in the proximal and distal convoluted tubules, but not in glomeruli nor collecting ducts.
Swiss-Prot Key

 

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