Anti-Phospho-MAK (Y159) antibody

Rs. 50,211.00
SKU stj90583

General Information

Product name Anti-Phospho-MAK (Y159) antibody
Short Description
Description Rabbit polyclonal to Phospho-MAK (Y159).
Applications WB,ELISA
Dilution range WB 1:500-1:2000ELISA 1:40000
Protein Name Anti-Phospho-MAK (Y159) antibody
Immunogen Synthesized peptide derived from human MAK around the phosphorylation site of Y159.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 85 kDa
Database Links
Alternative Names Phospho-MAK (Y159)
Serine/threonine-protein kinase MAK antibody
Male germ cell-associated kinase antibody
Function Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors . Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis. May play a role in chromosomal stability in prostate cancer cells.
Cellular Localization Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Midbody. Cell projection, cilium, photoreceptor outer segment Photoreceptor inner segment. Localized in both the connecting cilia and the outer segment axonemes . Localized uniformly in nuclei during interphase, to the mitotic spindle and centrosomes during metaphase and anaphase, and also to midbody at anaphase until telophase.
Tissue Specificity Expressed in prostate cancer cell lines at generally higher levels than in normal prostate epithelial cell lines. Isoform 1 is expressed in kidney, testis, lung, trachea, and retina. Isoform 2 is retina-specific where it is expressed in rod and cone photoreceptors.
Swiss-Prot Key

 

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