Anti-Phospho-NACA (S43) antibody

Rs. 50,211.00
SKU stj91263

General Information

Product name Anti-Phospho-NACA (S43) antibody
Short Description
Description Rabbit polyclonal to Phospho-NACA (S43).
Applications IHC,ELISA
Dilution range IHC 1:100-1:300ELISA 1:5000
Protein Name Anti-Phospho-NACA (S43) antibody
Immunogen Synthesized peptide derived from human NACA around the phosphorylation site of S43.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 23.384 kDa
Database Links
Alternative Names Phospho-NACA (S43)
Nascent polypeptide-associated complex subunit alpha antibody
NAC-alpha antibody
Alpha-NAC antibody
allergen Hom s 2 antibody
Function Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters.
Cellular Localization Cytoplasm. Nucleus. The heterodimer is located mainly in the cytosol, and the homodimer in the nucleus.
Tissue Specificity Ubiquitously expressed.
Swiss-Prot Key

 

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