Anti-Phospho-p130 Cas (Y249) antibody

Rs. 50,211.00
SKU stj90858

General Information

Product name Anti-Phospho-p130 Cas (Y249) antibody
Short Description
Description Rabbit polyclonal to Phospho-p130 Cas (Y249).
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000
Protein Name Anti-Phospho-p130 Cas (Y249) antibody
Immunogen Synthesized peptide derived from human p130 Cas around the phosphorylation site of Y249.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 130 kDa
Database Links
Alternative Names Phospho-p130 Cas (Y249)
Breast cancer anti-estrogen resistance protein 1 antibody
CRK-associated substrate antibody
Cas scaffolding protein family member 1 antibody
p130cas antibody
CAS antibody
CASS1 antibody
CRKAS antibody
Function Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.
Cellular Localization Cell junction, focal adhesion Cytoplasm. Unphosphorylated form localizes in the cytoplasm and can move to the membrane upon tyrosine phosphorylation.
Tissue Specificity Widely expressed with an abundant expression in the testis. Low level of expression seen in the liver, thymus, and peripheral blood leukocytes. The protein has been detected in a B-cell line.
Swiss-Prot Key

 

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