Anti-Phospho-PTP1B (S50) antibody

Rs. 50,211.00
SKU stj90882

General Information

Product name Anti-Phospho-PTP1B (S50) antibody
Short Description
Description Rabbit polyclonal to Phospho-PTP1B (S50).
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000
Protein Name Anti-Phospho-PTP1B (S50) antibody
Immunogen Synthesized peptide derived from human PTP1B around the phosphorylation site of S50.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat,Monkey
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 49 kDa
Database Links
Alternative Names Phospho-PTP1B (S50)
Tyrosine-protein phosphatase non-receptor type 1 antibody
Protein-tyrosine phosphatase 1B antibody
PTP-1B antibody
PTP1B antibody
Function Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
Cellular Localization Endoplasmic reticulum membrane. Interacts with EPHA3 at the cell membrane.
Tissue Specificity
Swiss-Prot Key

 

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