Anti-Phospho-SH-PTP1 (Y536) antibody

Rs. 50,211.00
SKU stj90740

General Information

Product name Anti-Phospho-SH-PTP1 (Y536) antibody
Short Description
Description Rabbit polyclonal to Phospho-SH-PTP1 (Y536).
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000
Protein Name Anti-Phospho-SH-PTP1 (Y536) antibody
Immunogen Synthesized peptide derived from human SH-PTP1 around the phosphorylation site of Y536.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 67 kDa
Database Links
Alternative Names Phospho-SH-PTP1 (Y536)
Tyrosine-protein phosphatase non-receptor type 6 antibody
Hematopoietic cell protein-tyrosine phosphatase antibody
Protein-tyrosine phosphatase 1C antibody
PTP-1C antibody
Protein-tyrosine phosphatase SHP-1 antibody
SH-PTP1 antibody
HCP antibody
PTP1C antibody
Function Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
Cellular Localization Cytoplasm. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin II . Shuttles between the cytoplasm and nucleus via its association with PDPK1.
Tissue Specificity Isoform 1 is expressed in hematopoietic cells. Isoform 2 is expressed in non-hematopoietic cells.
Swiss-Prot Key

 

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