Anti-Phospho-SPAK (S311) antibody

Rs. 50,211.00
SKU stj90959

General Information

Product name Anti-Phospho-SPAK (S311) antibody
Short Description
Description Rabbit polyclonal to Phospho-SPAK (S311).
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000
Protein Name Anti-Phospho-SPAK (S311) antibody
Immunogen Synthesized peptide derived from human SPAK around the phosphorylation site of S311.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 60 kDa
Database Links
Alternative Names Phospho-SPAK (S311)
STE20/SPS1-related proline-alanine-rich protein kinase antibody
Ste-20-related kinase antibody
DCHT antibody
Serine/threonine-protein kinase 39 antibody
SPAK antibody
Function May act as a mediator of stress-activated signals. Mediates the inhibiton of SLC4A4, SLC26A6 as well as CFTR activities by the WNK scaffolds, probably through phosphorylation.
Cellular Localization Cytoplasm Nucleus. Nucleus when caspase-cleaved.
Tissue Specificity Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis.
Swiss-Prot Key

 

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