Anti-Phospho-STAM2 (Y192) antibody

Rs. 50,211.00
SKU stj90559

General Information

Product name Anti-Phospho-STAM2 (Y192) antibody
Short Description
Description Rabbit polyclonal to Phospho-STAM2 (Y192).
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000
Protein Name Anti-Phospho-STAM2 (Y192) antibody
Immunogen Synthesized peptide derived from human STAM2 around the phosphorylation site of Y192.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 58 kDa
Database Links
Alternative Names Phospho-STAM2 (Y192)
Signal transducing adapter molecule 2 antibody
STAM-2 antibody
Hrs-binding protein antibody
HBP antibody
Function Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes .
Cellular Localization Cytoplasm Early endosome membrane
Tissue Specificity Ubiquitously expressed.
Swiss-Prot Key

 

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