Anti-Phospho-Synaptotagmin 1/2 (T202/199) antibody

Rs. 50,211.00
SKU stj90747

General Information

Product name Anti-Phospho-Synaptotagmin 1/2 (T202/199) antibody
Short Description
Description Rabbit polyclonal to Phospho-Synaptotagmin 1/2 (T202/199).
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000
Protein Name Anti-Phospho-Synaptotagmin 1/2 (T202/199) antibody
Immunogen Synthesized peptide derived from human Synaptotagmin 1/2 around the phosphorylation site of T202/199.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 60 kDa
Database Links
Alternative Names Phospho-Synaptotagmin 1/2 (T202/199)
Synaptotagmin-1 antibody
Synaptotagmin I antibody
SytI antibody
p65 antibody
SVP65 antibody
SYT antibody
Function May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes .
Cellular Localization Cytoplasmic vesicle, secretory vesicle membrane Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane Cytoplasm. Synaptic vesicles and chromaffin granules.
Tissue Specificity Expressed in melanocytes .
Swiss-Prot Key

 

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