Anti-Phospho-Vinculin (Y821) antibody

Rs. 50,211.00
SKU stj91311

General Information

Product name Anti-Phospho-Vinculin (Y821) antibody
Short Description
Description Rabbit polyclonal to Phospho-Vinculin (Y821).
Applications IHC,IF,ELISA
Dilution range IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000
Protein Name Anti-Phospho-Vinculin (Y821) antibody
Immunogen Synthesized peptide derived from human Vinculin around the phosphorylation site of Y821.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 123 kDa
Database Links
Alternative Names Phospho-Vinculin (Y821)
Vinculin antibody
Metavinculin antibody
MV antibody
Function Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
Cellular Localization Cell membrane Cell junction, adherens junction Cell junction, focal adhesion Cytoplasm, cytoskeleton. Recruitment to cell-cell junctions occurs in a myosin II-dependent manner. Interaction with CTNNB1 is necessary for its localization to the cell-cell junctions.
Tissue Specificity Metavinculin is muscle-specific.
Swiss-Prot Key

 

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