Anti-Phospho-WWOX (Y33) antibody

Rs. 50,211.00
SKU stj90971

General Information

Product name Anti-Phospho-WWOX (Y33) antibody
Short Description
Description Rabbit polyclonal to Phospho-WWOX (Y33).
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000
Protein Name Anti-Phospho-WWOX (Y33) antibody
Immunogen Synthesized peptide derived from human WWOX around the phosphorylation site of Y33.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 55 kDa
Database Links
Alternative Names Phospho-WWOX (Y33)
WW Domain Containing Oxidoreductase antibody
Short Chain Dehydrogenase/Reductase Family 41C Member antibody
WW Domain-Containing Oxidoreductase antibody
Fragile Site FRA16D Oxidoreductase antibody
SDR41C1 antibody
WOX1 antibody
FOR antibody
Short Chain Dehydrogenase/Reductase Family 41C antibody
Member 1 antibody
WW Domain-Containing Protein WWOX antibody
EC 1.1.1.- antibody
D16S432E antibody
EC 1.1.1 antibody
HCMA56 antibody
PRO0128 antibody
EIEE28 antibody
FRA16D antibody
SCAR12 antibody
FOR antibody
SDR41C1 antibody
WOX1 antibody
Function Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development . May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.
Cellular Localization Cytoplasm Nucleus Mitochondrion Golgi apparatus. Partially localizes to the mitochondria . Translocates to the nucleus upon genotoxic stress or TNF stimulation . Translocates to the nucleus in response to TGFB1 . Isoform 5 and isoform 6 may localize in the nucleus.
Tissue Specificity Widely expressed. Strongly expressed in testis, prostate, and ovary. Overexpressed in cancer cell lines. Isoform 5 and isoform 6 may only be expressed in tumor cell lines.
Swiss-Prot Key

 

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