Anti-PIEZO1 Antibody

Rs. 45,619.00
SKU stj26627

General Information

Product name Anti-PIEZO1 Antibody
Short Description Rabbit polyclonal to PIEZO1
Description The protein encoded by this gene is a mechanically-activated ion channel that links mechanical forces to biological signals. The encoded protein contains 36 transmembrane domains and functions as a homotetramer. Defects in this gene have been associated with dehydrated hereditary stomatocytosis.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-PIEZO1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 2230-2420 of human PIEZO1 (NP_001136336.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 286.8 kDa
Database Links
Alternative Names PIEZO1Piezo-type mechanosensitive ion channel component 1 antibodyMembrane protein induced by beta-amyloid treatment antibodyMib antibodyProtein FAM38APIEZO1 antibodyFAM38A antibodyKIAA0233
Function Pore-forming subunit of a mechanosensitive non-specific cation channel.
Cellular Localization Endoplasmic reticulum membrane.
Tissue Specificity Expressed in numerous tissues, in normal brain, expressed exclusively in neurons, not in astrocytes, in alzheimer disease brains, expressed in about half of the activated astrocytes located around classical senile plaques, in parkinson disease substantia nigra, not detected in melanin-containing neurons nor in activated astrocytes, expressed in erythrocytes (at protein level).
Swiss-Prot Key

 

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