Anti-PIGA Antibody

Rs. 45,619.00
SKU stj27992

General Information

Product name Anti-PIGA Antibody
Short Description Rabbit polyclonal to PIGA
Description This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-PIGA Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human PIGA (NP_002632.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 54.1 kDa
Database Links
Alternative Names PIGAPhosphatidylinositol N-acetylglucosaminyltransferase subunit A PIGA
Function Necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis
Cellular Localization Endoplasmic reticulum membrane
Tissue Specificity
Swiss-Prot Key

 

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