Anti-PINK1 Antibody

Rs. 45,619.00
SKU stj29211

General Information

Product name Anti-PINK1 Antibody
Short Description Rabbit polyclonal to PINK1
Description This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-PINK1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 282-581 of human PINK1 (NP_115785.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 62.8 kDa
Database Links
Alternative Names PINK1Serine/threonine-protein kinase PINK1 antibodymitochondrial PINK1
Function Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins, Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PRKN.
Cellular Localization Mitochondrion outer membrane
Tissue Specificity Highly expressed in heart, skeletal muscle and testis, and at lower levels in brain, placenta, liver, kidney, pancreas, prostate, ovary and small intestine, present in the embryonic testis from an early stage of development.
Swiss-Prot Key

 

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