Anti-PITX2 Antibody

Rs. 45,619.00
SKU stj25006

General Information

Product name Anti-PITX2 Antibody
Short Description Rabbit polyclonal to PITX2
Description This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-PITX2 Antibody
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PITX2 (NP_000316.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 35.4 kDa
Database Links
Alternative Names PITX2Pituitary homeobox 2 antibodyALL1-responsive protein ARP1 antibodyHomeobox protein PITX2 antibodyPaired-like homeodomain transcription factor 2 antibodyRIEG bicoid-related homeobox transcription factor antibodySolurshinPITX2 antibodyARP1 antibodyRGS antibodyRIEG antibodyRIEG1
Function Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis, During embryonic development, exerts a role in the expansion of muscle progenitors, May play a role in the proper localization of asymmetric organs such as the heart and stomach, Isoform PTX2C is involved in left-right asymmetry the developing embryo (By similarity).
Cellular Localization Nucleus
Tissue Specificity
Swiss-Prot Key

 

You recently viewed

Clear recently viewed
Print Friendly and PDF