Anti-PJA2 Antibody

Rs. 45,619.00
SKU stj28527

General Information

Product name Anti-PJA2 Antibody
Short Description Rabbit polyclonal to PJA2
Description
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:100
Protein Name Anti-PJA2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 439-708 of human PJA2 (NP_055634.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 78.2 kDa
Database Links
Alternative Names PJA2E3 ubiquitin-protein ligase Praja-2 antibodyPraja2PJA2 antibodyKIAA0438 antibodyRNF131
Function Has E2-dependent E3 ubiquitin-protein ligase activity, Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation, Essential for PKA-mediated long-term memory processes, Through the ubiquitination of MFHAS1, positively regulates the TLR2 signaling pathway that leads to the activation of the downstream p38 and JNK MAP kinases and promotes the polarization of macrophages toward the pro-inflammatory M1 phenotype.
Cellular Localization Cytoplasm.
Tissue Specificity
Swiss-Prot Key

 

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