Anti-PKD2 Antibody

Rs. 45,619.00
SKU stj25010

General Information

Product name Anti-PKD2 Antibody
Short Description Rabbit polyclonal to PKD2
Description This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Anti-PKD2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 240-410 of human PKD2 (NP_000288.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 109.7 kDa
Database Links
Alternative Names PKD2Polycystin-2 antibodyPC2 antibodyAutosomal dominant polycystic kidney disease type II protein antibodyPolycystic kidney disease 2 protein antibodyPolycystwin antibodyR48321 antibodyTransient receptor potential cation channel subfamily P member 2PKD2 antibodyTRPP2
Function Functions as a cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium.
Cellular Localization Cell projection, cilium membrane.
Tissue Specificity Detected in fetal and adult kidney , strongly expressed in ovary, fetal and adult kidney, testis, and small intestine, not detected in peripheral leukocytes.
Swiss-Prot Key

 

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