Anti-PKP2 Antibody

Rs. 45,619.00
SKU stj27458

General Information

Product name Anti-PKP2 Antibody
Short Description Rabbit polyclonal to PKP2
Description This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-PKP2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 578-837 of human PKP2 (NP_001005242.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 97.4 kDa
Database Links
Alternative Names PKP2Plakophilin-2PKP2
Function May play a role in junctional plaques.
Cellular Localization Nucleus.
Tissue Specificity Detected in heart right ventricle (at protein level), widely expressed, found at desmosomal plaques in simple and stratified epithelia and in non-epithelial tissues such as myocardium and lymph node follicles, in most stratified epithelia found in the desmosomes of the basal cell layer and seems to be absent from suprabasal strata.
Swiss-Prot Key

 

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