Anti-PLAU Antibody

Rs. 45,619.00
SKU stj25021

General Information

Product name Anti-PLAU Antibody
Short Description Rabbit polyclonal to PLAU
Description This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-PLAU Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 20-180 of human PLAU (NP_002649.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 48.5 kDa
Database Links
Alternative Names PLAUUrokinase-type plasminogen activator antibodyU-plasminogen activator antibodyuPAPLAU
Function Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin
Cellular Localization Secreted
Tissue Specificity Expressed in the prostate gland and prostate cancers.
Swiss-Prot Key

 

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