Anti-PLG Antibody

Rs. 61,689.00
SKU stj28270

General Information

Product name Anti-PLG Antibody
Short Description Rabbit polyclonal to PLG
Description The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Anti-PLG Antibody
Immunogen A synthetic peptide of human PLG
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 90.6 kDa
Database Links
Alternative Names PLGPlasminogenPLG
Function Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation, In ovulation, weakens the walls of the Graafian follicle, It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5, Cleavage of fibronectin and laminin leads to cell detachment and apoptosis, Also cleaves fibrin, thrombospondin and von Willebrand factor, Its role in tissue remodeling and tumor invasion may be modulated by CSPG4, Binds to cells.
Cellular Localization Secreted.
Tissue Specificity Present in plasma and many other extracellular fluids, it is synthesized in the liver
Swiss-Prot Key

 

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