Anti-POLB Antibody

Rs. 45,619.00
SKU stj25039

General Information

Product name Anti-POLB Antibody
Short Description Rabbit polyclonal to POLB
Description The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date.
Applications WB,IF
Dilution range WB 1:200 - 1:1000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Anti-POLB Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human POLB (NP_002681.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 38.2 kDa
Database Links
Alternative Names POLBDNA polymerase beta POLB
Function Repair polymerase that plays a key role in base-excision repair, Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap, Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
Cellular Localization Nucleus, Cytoplasm.
Tissue Specificity
Swiss-Prot Key

 

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