Anti-PPBP Antibody

Rs. 45,619.00
SKU stj25071

General Information

Product name Anti-PPBP Antibody
Short Description Rabbit polyclonal to PPBP
Description The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity.
Applications WB,IHC
Dilution range WB 1:500 - 1:1000
IHC 1:50 - 1:100
Protein Name Anti-PPBP Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 31-128 of human PPBP (NP_002695.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 13.9 kDa
Database Links
Alternative Names PPBPPlatelet basic protein antibodyPBP antibodyC-X-C motif chemokine 7 antibodyLeukocyte-derived growth factor antibodyLDGF antibodyMacrophage-derived growth factor antibodyMDGF antibodySmall-inducible cytokine B7PPBP antibodyCTAP3 antibodyCXCL7 antibodySCYB7 antibodyTGB1 antibodyTHBGB1
Function LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan, It also stimulates the formation and secretion of plasminogen activator by human synovial cells, NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils, TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules, CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.
Cellular Localization Secreted
Tissue Specificity
Swiss-Prot Key

 

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