Anti-PPFIA1 Antibody

Rs. 61,689.00
SKU stj25072

General Information

Product name Anti-PPFIA1 Antibody
Short Description Rabbit polyclonal to PPFIA1
Description The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Anti-PPFIA1 Antibody
Immunogen A synthetic Peptide of human PPFIA1
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 135.8 kDa
Database Links
Alternative Names PPFIA1Liprin-alpha-1 antibodyLAR-interacting protein 1 antibodyLIP-1 antibodyProtein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1 antibodyPTPRF-interacting protein alpha-1PPFIA1 antibodyLIP1
Function May regulate the disassembly of focal adhesions, May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
Cellular Localization Cytoplasm.
Tissue Specificity Ubiquitous.
Swiss-Prot Key

 

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