Anti-PRPF19 Antibody

Rs. 61,689.00
SKU stj25160

General Information

Product name Anti-PRPF19 Antibody
Short Description Rabbit polyclonal to PRPF19
Description
Applications WB,IHC,FC
Dilution range WB 1:1000 - 1:2000
IHC 1:50 - 1:200
FC 1:20 - 1:50
Protein Name Anti-PRPF19 Antibody
Immunogen A synthetic peptide of human PRPF19
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 55.2 kDa
Database Links
Alternative Names PRPF19Pre-mRNA-processing factor 19 PRPF19 antibodyNMP200 antibodyPRP19 antibodySNEV
Function Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair, Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity, During assembly of the spliceosome, mediates 'Lys-63'-linked polyubiquitination of the U4 spliceosomal protein PRPF3, Ubiquitination of PRPF3 allows its recognition by the U5 component PRPF8 and stabilizes the U4/U5/U6 tri-snRNP spliceosomal complex.
Cellular Localization Nucleus
Tissue Specificity Ubiquitous, weakly expressed in senescent cells of different tissue origins, highly expressed in tumor cell lines.
Swiss-Prot Key

 

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