Anti-PRPF8 Antibody

Rs. 45,619.00
SKU stj27847

General Information

Product name Anti-PRPF8 Antibody
Short Description Rabbit polyclonal to PRPF8
Description Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:1000
IHC 1:50 - 1:100
IF 1:50 - 1:100
IP 1:50 - 1:100
Protein Name Anti-PRPF8 Antibody
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PRPF8 (NP_006436.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 273.6 kDa
Database Links
Alternative Names PRPF8Pre-mRNA-processing-splicing factor 8 antibody220 kDa U5 snRNP-specific protein antibodyPRP8 homolog antibodySplicing factor Prp8 antibodyp220PRPF8 antibodyPRPC8
Function Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs, Required for the assembly of the U4/U6-U5 tri-snRNP complex, Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur, Interacts with both the 5' and the 3' splice site.
Cellular Localization Nucleus speckle
Tissue Specificity Widely expressed.
Swiss-Prot Key

 

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