Anti-PSRC1 Antibody

Rs. 45,619.00
SKU stj27437

General Information

Product name Anti-PSRC1 Antibody
Short Description Rabbit polyclonal to PSRC1
Description This gene encodes a proline-rich protein that is a target for regulation by the tumor suppressor protein p53. The encoded protein plays an important role in mitosis by recruiting and regulating microtubule depolymerases that destabalize microtubules. Alternatively spliced transcript variants encoding different isoforms have been described.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-PSRC1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human PSRC1 (NP_001005290.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 38.8 kDa
Database Links
Alternative Names PSRC1Proline/serine-rich coiled-coil protein 1PSRC1 antibodyDDA3 antibodyFP3214
Function Required for normal progression through mitosis, Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase, Plays a role in the regulation of mitotic spindle dynamics, Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores, Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles, May participate in p53/TP53-regulated growth suppression.
Cellular Localization Cytoplasm, Cytoplasm, cytoskeleton, spindle, Cytoplasm, cytoskeleton, spindle pole.
Tissue Specificity Widely expressed in adult and fetal tissues, with highest expression in the adult brain and fetal thymus, not detected in adult skeletal muscle.
Swiss-Prot Key

 

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