Anti-Ptgds Antibody

Rs. 68,577.00
SKU stj72754

General Information

Product name Anti-Ptgds Antibody
Short Description Goat polyclonal to Ptgds (mouse)
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-Ptgds Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 21.1 kDa
Database Links
Alternative Names Anti-Ptgds (mouse) Antibody
Function Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes, Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter, Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier, It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system,
Cellular Localization Rough endoplasmic reticulum,
Tissue Specificity Abundant in the brain and cns, where it is expressed in tissues of the blood-brain barrier and secreted into the cerebro-spinal fluid, in the male reproductive system, it is expressed in the testis, efferent ducts and epididymis, and is secreted into the seminal fluid, in the eye, it is expressed in the pigmented epithelium of the retina and the nonpigmented epithelium of the ciliary body, and secreted into the aqueous humor, low levels detected in various tissue fluids such as serum, normal urine, ascitic fluid and tear fluid, also found in a number of other organs including the ear, heart and lung,
Swiss-Prot Key

 

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