Anti-PTGS1 Antibody

Rs. 45,619.00
SKU stj29480

General Information

Product name Anti-PTGS1 Antibody
Short Description Rabbit polyclonal to PTGS1
Description This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:100 - 1:200
Protein Name Anti-PTGS1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human PTGS1 (NP_001258094.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 68.7 kDa
Database Links
Alternative Names PTGS1Prostaglandin G/H synthase 1 PTGS1 antibodyCOX1
Function Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis, Involved in the constitutive production of prostanoids in particular in the stomach and platelets, In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection, In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells
Cellular Localization Microsome membrane
Tissue Specificity
Swiss-Prot Key

 

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