Anti-Rab17 Antibody

Rs. 68,577.00
SKU stj71451

General Information

Product name Anti-Rab17 Antibody
Short Description Goat polyclonal to Rab17 (mouse)
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-Rab17 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 23.6 kDa
Database Links
Alternative Names Anti-Rab17 (mouse) Antibody
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes, Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion, That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side, Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface, Most probably controls membrane trafficking through apical recycling endosomes in a post-endocytic step of transcytosis, Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development, May also play a role in cell migration,
Cellular Localization Recycling endosome membrane,
Tissue Specificity Expressed in kidney, liver, and intestine mainly by epithelial cells, expressed in hippocampus (at protein level),
Swiss-Prot Key

 

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