Anti-RAB31 Antibody

Rs. 45,619.00
SKU stj29642

General Information

Product name Anti-RAB31 Antibody
Short Description Rabbit polyclonal to RAB31
Description
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-RAB31 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human RAB31 (NP_006859.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 21.6 kDa
Database Links
Alternative Names RAB31Ras-related protein Rab-31 antibodyRas-related protein Rab-22BRAB31 antibodyRAB22B
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes, Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion, Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network, Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane, Plays a role in M6PR transport from the trans-Golgi network to endosomes, Plays a role in the internalization of EGFR from the cell membrane into endosomes, Plays a role in the maturation of phagosomes that engulf pathogens, such as S,aureus and M,tuberculosis.
Cellular Localization Golgi apparatus, trans-Golgi network.
Tissue Specificity Highest expression in placenta and brain with lower levels in heart and lung, not detected in liver, skeletal muscle, kidney or pancreas.
Swiss-Prot Key

 

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