Anti-RAB6A Antibody

Rs. 45,619.00
SKU stj27580

General Information

Product name Anti-RAB6A Antibody
Short Description Rabbit polyclonal to RAB6A
Description This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
Protein Name Anti-RAB6A Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human RAB6A (NP_002860.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 23.6 kDa
Database Links
Alternative Names RAB6ARas-related protein Rab-6A antibodyRab-6RAB6A antibodyRAB6
Function Protein transport, Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER), Has a low GTPase activity, Involved in COPI-independent retrograde transport from the Golgi to the ER.
Cellular Localization Golgi apparatus membrane
Tissue Specificity Ubiquitous.
Swiss-Prot Key

 

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