Anti-RBBP7 Antibody

Rs. 45,619.00
SKU stj29047

General Information

Product name Anti-RBBP7 Antibody
Short Description Rabbit polyclonal to RBBP7
Description This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
Applications WB,IF,IP,ChIP
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:100
IP 1:50 - 1:200
ChIP 1:50 - 1:200
Protein Name Anti-RBBP7 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human RBBP7 (NP_002884.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 47.8 kDa
Database Links
Alternative Names RBBP7Histone-binding protein RBBP7 antibodyHistone acetyltransferase type B subunit 2 antibodyNucleosome-remodeling factor subunit RBAP46 antibodyRetinoblastoma-binding protein 7 antibodyRBBP-7 antibodyRetinoblastoma-binding protein p46RBBP7 antibodyRBAP46
Function Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA, Component of several complexes which regulate chromatin metabolism, These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication
Cellular Localization Nucleus
Tissue Specificity
Swiss-Prot Key

 

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